I get the hunting big critters, I just don't get 330gr bullets. PARTICULARLY in an autoloader that wasn't designed for them. You can, in a revolver, load out to flush with the face of the cylinder, if you want, and get some extra length, for the uber heavy bullet to fit in. You cannot do that with an autopistol, unless you plan on single loading each long round, and that defeats the purpose of an autoloader.
If you want to shoot 300gr + slugs, get a Contender in .45-70.
I've shot (and still have a couple boxes) of the Win 230gr "ball" FMJ .45 Win Mag. Hot stuff, but not a good bullet for hunting. Win also made a 260gr JHP which was a much better big game bullet.