I've never seen any evidence showing the type of ammo used made a difference in the final outcome of a trial.
There has been such a case. I don't have the cite handy, but if you search the Handload/selfdefense threads you will find it.
The real boogeyman to worry about isn't the oft stated fear about the prosecutor trying to turn you into a killer because you loaded "extra deadly" ammo. That has been tried, numerous times, and so far, has never worked.
The case I'm talking about did result in a conviction, essentially because of a handload, and the forensic lab's
interpretation of the evidence. Guy said wife was despondent, tried to shoot herself. He tried to stop her. Struggle over the gun, it goes off, she died. Tragic accident.
Lab looks at powder spray pattern, and says, "No, not enough powder residue for point blank shot. Shot came from across the room. Husband is lying. The Jury went with the lab's story, and convicted.
The ammo came from a box of mixed handloads. Even if it had been in a box with all components marked, it still would have been a problem, because literally, its only your word what the ammo is, and since you are in court, your word is suspect, automatically.
Any handloader knows that you will get a drastically different result from a charge of Bullseye than you do from a charge of 2400 powder. But lab analysis requires a standard to judge against. The common standard is factory ammo (of the same lot#, when known).
This is the point to be concerned about. A good shoot, the ammo won't matter. If you wind up in court, something is questionable, and your word isn't enough. What will matter is other people's opinions, and while in most situations, a handload will not matter, it is possible it might, in the eyes of others.
Standard .45 Colt, the traditional load with a 255gr bullet at black powder speeds was used by the Army to stop men and horses. It worked. In fact, the Army actually used more of a lighter load (.45 Army /.45 Schoefield), the ballistics of which were used as required the specs for the .45 Auto round when it was being considered for adoption.
The British .455 Webley used a 265gr lead slug at 600fps, and was considered to be an adequate manstopper. (but then, what do the English know?
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Placement is what matters most, and the .45 Colt in standard trim had all the oomph needed, if you do your part right.