BE-86
Frankly, Universal is not the best powder for 45 ACP. I reload 45 ACP, 40 S&W and 9mm. I have compared, purchased and loaded: Bullseye, Power Pistol, BE-86, Unique, Longshot, CFE Pistol, Silhouette, WSF; in these calibers. Not necessarily every possible combination.
I use the hodgdonreloading.com/reloading-data-center, alliantpowder.com, Speer Bullets online data, a Lyman manual, and other online reloading data sources. That is how I decided I needed these powders. Universal is not one of them, is middling, and not a race horse for pistol calibers. The ones I listed will get you highest velocity in at least one caliber and bullet weight.
Plug your specs in at HDC and compare the results of differing powders they display in an easy to read table. You wont find Universal as a velocity leader.
So, you are asking how do I get maximum performance from a powder not up to the task. You don't. You should buy a pound of BE-86; which is also flash suppressed. If I could only use one pistol powder BE-86 is it. One pound will load about 1000 rounds (@ 7 gr. per round).