Hmmm, real difficult choice. NOT!!!
Let's see. Buy 38 special just about anyplace. Quite available. $14-$18 a box. Be able to practice all I want. Possibly even make it a 357mag revolver just in case I wanted a 2nd caliber to shoot.
Or
Look all over town for 380. MAYBE find some. Possibly find some defensive ammo for about $25-$30. If I'm lucky, I might find some plinking ammo for $20-$22 a box. Practice rarely because of the lack and price of ammo.
Hmmmm. Which one should I get??? Do I really have to answer that. Years ago, when the 380 ammo wasn't an issue, it had it's place. It was a semi-auto for those who didn't like revolvers. The ammo was the same price as 9mm and 32acp. It didn't kick quite as much as 9mm; however the 380 was usually in a smaller gun so the kick increased. But, the concealability was better. 9mm Mak wasn't too available. So yes, the 380 was definitely a viable choice.
Today: 32acp, 9mm mak, and 9mm are all less expensive. More ammo technology has made the 32acp almost as powerful. In some ammo, MORE powerful. 9mm mak is very available, pistols are cheaper and great military quality, and ammo is really cheap. Plus, many of the guns are about as small as the 380's and 32acp. More 9mm luger have gotten smaller. That ammo is definitely available and cheaper. Personally, if I didn't own a 380, there is absolutely nothing that could convince me to get a gun in that caliber. Especially considering how many of the guns are the same size chambered in 9mm. There is nothing logical about getting a 380. A 38spl is definitely a better choice. If you really think that a revolver is not a good self defense gun, and you can't get over the bad information someone convinced you about, then there are plenty of other options in the semi-auto world besides a 380. Right now, the 380 is the LAST caliber I'd buy. Well, maybe not the last. There are other "FOO FOO" calibers that have less use like the 45gap, 357sig, and the 10mm. Outside of those and a couple others, the 380 is definitely at the bottom of the list of calibers to buy. There's just nothing logical about it.