Personally I like the S&W13 (a PC job) for carry. It is a small light K frame with a 3 inch barrel that will handle 357 Mags just fine.
My wife will never give up her 586 with a 4 inch barrel. And no one would want to be a bad guy on the receiving end of that revolver, she just don't miss! For practice she likes 38+p, and can shoot them all day long without the recoil bugging her.
IMHO, For home defense the 38+p rounds are really just about right. With the bullets we select over penetration is not a problem but you still have more than enough gun to get a perps attention.
In the woods, we both use 357. k