This is my first post so be gentle. I love Ruger handguns. I own 5 of them. I love 4 of them and like the other very well. BUT, Ruger often misses the mark when it comes to the handgun of my dreams. Like many of you have said, I would have purchases a LCRx in a 3" barrel IF it had adjustable rear sight, or at the very least "driftable" rear sights. Like others, I emailed Ruger about my desires and got the pat response "we have no plans of producing that firearm."
I "settled" for a SP101 Wiley Clap, 357 mag with a 2.25" barrel. I'm extremely happy with this revolver. I carry it daily. My 5th cylinder full, I shot two 10's, two 9's and a 6 (which I knew was left and low at the trigger pull). That was at 7 yards. I love this gun.
As far as a .22 cal in an LCR with a 3 inch barrel is concerned, I see the appeal, but I'm extremely happy with the Mark III that I've owned for 35+ years. I've probably taken more game with that pistol than I have with all the other non-shotgun firearms I own, combined. It lives in my glove box.
Now if Ruger made a LCRx in a .22 magnum they'd have my attention.