I've shot several pigs, most over 180 pounds. The worst performance was from a 44 mag revolver, trying to finish one off from 25 feet. The bullet was the problem: a Remington HSP with the scalloped jacket did not penetrate the gristle plate. The hog died, but it must have been from the shock effect. I've since gone to 250 gr Sierra silhouette loads with a little dimple of exposed lead. They expand on a pig's shoulder but still punch through. I have used 180 gr corelokts in both a 30-06 and a 300 mag, and they worked great. The 300 mag was mainly used for long range in the barley fields, not for increased power. The main thing is to try to kill them with a good first shot. Once wounded, they take a lot of killing! Noslers also work well, but did not seem to be required on pigs up to 300 lbs.