I have a 20SF and a Glock 22 - my chrono averages for at least 5 shots
Glock 22: Factory load Speer Gold Dot 180 gr. @ 975 fps / 380# KE
Glock 20SF: Handload 180 gr. Gold Dot @ 1,146 fps / 525#
What does the additional 171 fps / 145# (+28%) KE do?
In water filled gallon jugs with 4 layer denim in front:
40 S&W penetrates to rear of 4th jug and expands .64
10mm handload penetrates to rear of 3rd jug, dents 4th and expands to .75
Additional velocity expands the bullet to larger diameter which actually reduces penetration.
Would this matter for SD? IDK
The rest is not specifically for OP question but needs addressed, IME
Why did I not load the 10mm hotter? 2nd shot / follow up shot time.
Anyone that has actually shot a Glock 21SF (45 acp) probably regarded it as "soft shooting" and it is.
10mm recoil can be controlled so that although it feels different from 45 acp it doesn't have a negative effect on 2nd shot time.
Since the pistols are the same size with same grip ect... a valid comparison can be made.
http://www.shooterscalculator.com/recoil-calculator.php
1.8# firearm weight for Glock 20/21
Powder charge assigned to factory load based on max charge #5 from AA load manual, reasonable guess. 10mm charge actual used.
Glock 20: Handload 180 gr. Gold Dot @ 1,146 fps / 525# KE - recoil energy 11.2 / PF 206
Glock 21: Federal HST 230 gr. @ 863 fps / 380# KE - recoil energy 11.1 / PF 198
I think recoil energy best matches my subjective impression, but I included the power factor PF as well.
20SF with 180 Gold Dot offers two more rounds capacity and 28% more KE than the 21SF in 45, with a similar level of felt recoil.
I don't know which is "better".
Somebody is thinking,
"But muh 10mm power, that doesn't seem full power"
My 180 Gold Dot handload produces power (KE) on par with original self defense load, 10mm Silvertip, averaged 1,170 fps / 533# from a Glock 20SF
https://www.youtube.com/watch?v=RmNL30om6Eo
For the "KE don't matter at handgun levels" people:
http://www.luckygunner.com/labs/self-defense-ammo-ballistic-tests/
Both of these meet 12-18'' penetration goal and expand, same starting diameter bullet, similar penetration, similar recovered diameter.
380 Hornady FTX Critical Defense 13.2'' / .52 (90 gr. @ 910 fps = 165# KE)
9mm Corbon JHP 13.6'' / .56 (115 gr. @ 1,221 fps = 381# KE)
"KE don't matter" people should be equally content to bet their life on the incapacitation potential of the 380 as the 9mm +P
(I wouldn't).