biggest animal i have hunted ; whitetail deer
it's an age old arguement, but i think it boils down to bullet placement. i have personally killed 46 deer with a 220 swift, all one shot, all fell in their tracks, even accidently killed two in one shot with it. you know the swift; one of those 22 caliber guns that can't be relied on to humanely kill. how many shooters of the larger calibers can say they have killed 46 in a row and never had one leave his tracks? i have also kiled 7 with a 243, same results. i have loaned the same rifle to friends i have taken hunting, who don't practice with this or any rifle and had to track down the deer and shoot them again. same people squawked and blamed the 243, give em a 7 mag or 30-06 and it's worse. the 243 is a fine cartridge, just as any other, when you do your part.
i use a 243 with winchester 55 grain supremes to hunt coyotes and just love it. also with these light fast bullets shoot through and richochets are less of a problem.
sighting in is fun, shoot a terget on a cardboard box, bullet explodes on one side of the box, hits the other like a grenade.