I know there a better calibers to choose for hunting medium game and I do own a S&W 629 when it is the primary choice.....however, my 4" barreled S&W 627 is a little handier when carrying a rifle along so if I get a reasonable shot at a deer I might consider trying it out ! Anyway , for those that have used the .357 on deer or other medium game what are some of your favorite factory or handloads ? Thanks much ! I don't have reloading dies yet for the .357 but have some Federal 158 grain soft point ammo on hand and sighted in at 25 yards so far and want to practice out to 50 yards ! I ordered some Buffalo Bore 180 grain hardcast ammo to try out as well.....maybe handloading a hardcast 180 grain might be the way to go ( just thinking out loud ) !