It likely depends on the individual weapon, but i used to buy 155 grain LSWC's and reload them. Fun stuff-with 5 grains of 231, it was like a squirt gun and it helps to learn the trigger while having just enough to cycle the slide with no recoil to speak of.
Just for fun, I loaded some to boy-howdy max., and that was quite a display of muzzle flash. Tried them both at 3 to 25 yards with no key holing, but never shot a live creature with that bullet, so I can't say what penetration would be like. SD is absolute, assuming equal velocities and bullet styles, so I don't think they would go very far into the game.
I shot some over a chrono and got 1300+fps out of a government model.