KMax,
Here's the kicker...yes, Ruger .45LC throats are sometimes too tight. OK, they're too tight a lot of the time
. But the chambers are generally right and right, and uniform between chambers (as long as we're talking about a mid-frame from 2004 forward (mainly New Vaquero) OR a large-frame made after the 2007 switchover in the cylinder making process.
You can identify the new improved cylinders on the large-frames by where the "lawyer's warning label" on the barrel is. Under-barrel is new (good), side-barrel is old. The new process had all the chambers done with the same bit/reamer set in sequence rather than the old six-at-once process that produced too many mis-matched chambers in a single cylinder
.
The "tight throats" issue is annoying. But the more common case with Ubertis is an oversize chamber and that's a lot worse. Undersize you can fix (for cheap at cylindersmith.com!) while oversize...yeah, not so much.
What I recommend is, get a dual-caliber 45LC/45ACP variant. Blued full-size Blackhawks in 4.68" and 5.5" are standard catalog run, stainless are available in special distributor runs...there's one right now through Lipsey's. I'd just go with blue though, myself...for one thing, they're lighter in the large-frames because the grip frame is aluminum.
You can also find dual-caliber mid-frame New Vaqueros right now via Davidson's:
http://ruger.com/products/vaqueroDE/models.html
...BUT note that a mid-frame is only good to loads of around 22k PSI max, much like an Uberti or a post-WW2 Colt SAA. The large-frames in 45LC are good to 33k and some factory loads exceed 44Magnum power levels
.
In my view, the best bang for the buck in a single action wheelgun today is a new-made Ruger large-frame Blackhawk in 45LC/45ACP convertible, blue, standard catalog gun. It's lighter than a mid-frame variant, strong enough to rival a 44Mag, very flexible in terms of ammo type, power and cost. Also a good platform for "modding" - alter the hammer, grips and whatever else you want to your needs.
When I was shopping in 2005 that's what I wanted, except the cylinders weren't built as well as the mid-frame New Vaqueros. So I ended up modifying the hell out of a NewVaq357, including sights better than anything found on a stock Ruger handgun period. I'm now converting it to 9mmPara with magazine feeding and gas-powered auto-ejection of empty shells so...it's on the way to being the most heavily modded Ruger SA in history
.
Ah yes...you asked about 357 accuracy vs. 45. I suspect the 45 is the more accurate round with some effective handloading and properly reamed throats. And the 45ACP's accuracy isn't bad either - both are meant to shoot through the same barrel specs so there's little if any accuracy loss in 45ACP. In the 357Mag/9mm convertibles, 9mm ammo is actually supposed to get shot through a .355" barrel so there's an accuracy loss when you switch calibers. Not so with the dual 45 setup.