Yep. We have a rem 788 in .243 that I use, and a rem 600 in 6mm that my brothers use. They work good on deer.
My brothers first deer(muley doe), with the 6mm. It was trotting up a hill at 150. One shot to the neck dropped it, but it jumped back up and was making a dash for a valley that dropped off like hells canyon. Two more shots broke a front leg, and took out the lungs. Using 100gr federals. The post mortem showed that the shot throuch the neck hit nothing but meat!!! It just grazed under the fur and knicked some muscle, just enough to knock him down. (est. 180 lbs)
My first (black tail buck) was with the .243 From about 130 above him (45 degree hill) I hit him running through both hips and cut both arterys in the legs. (I was running, not him....long story) HE went down behind this giant log, and we had to go down and find him. One shot in the neck killed him. He was lieing right where I hit him in what looked like 20 gallons of blood. Inside he was dry, he would have bled to death in less than 5 minutes.(est 170 lbs)
My second deer(blacktail doe) .243, She ran out and stood on the logging road about 20 yards from us. One through the lungs (and far shoulder, cuz she was standing at an angle) and she dropped like a rock. (est 120 lbs)
I love our little 6mm and .243, they double as our long range varmint guns. The heavier bullets fly further without getting knocked around by the wind, and loosing their punch.
I shot 2 fox last year with the 6mm, 100 gr. One at about 30yrds had a 7 inch exit (it sewed up nicely) and one at about 100yrds had a fifty cent piece size exit, but it stretched to about 4" while skinning, but sewed up good too.
I heard somebody on these forum talk about only using the .243 "inside of 50 yards" on deer. That's BS. I'd use both these guns out to 300, or further if I thought I could make the shot. They're flat shooting, and fast, and don't kick much, that makes for excellent kids/ladies guns, and they're great for varmints too.