Jevyod asked:
What kind of Extreme spread is acceptable?
Whatever is acceptable to you.
As you fired each round through the chronograph, did you note where it impacted the target?
Also, are the velocities in your string clustered around a particular velocity with a single outlier creating the spread, or is the distribution of velocities pretty well spread out? In statistical terms, what was your mean, median, mode and what was the standard deviation of the string?
If the velocity differences are not impacting your point of impact and they were pretty well distributed throughout your range then I would ignore spreads of 40 or 65 fps.
If you had nine rounds all within 10 fps of one another and then one that was 55 fps out, AND the 55 fps outlier hit the target well away from the other rounds than you might want to throw some charges to the pan on your scale and see if you need to work on your powder measure, otherwise ignore it.
I throw all my charges to the scale and then trickle up to weight so I know my charges are consistent and even so I once loaded a string of 223 Remington rounds that produced an extreme spread of 254 fps. I attribute the spread to the fact the cheap FMJs I was shooting had significant variability in dimensions. Still, at 100 yards, all the rounds were within a 1.5 inch circle and I was firing offhand, not from a bench, so I said that was good enough for what I needed to do.