I'd go with the Rottweil Brenneke, the usual sources on the Netvine tell me wildife pros use this as load of choice when tranporting "Problem" bears. Sometimes they mix load with 00.
The 2 3/4", 1 1/4 oz slug has tremendous penetration and a big wound channel all the way through deer.If you hold the critter up to the light right, you can darn near see through the hole.