One of the more versatile revolvers would be a S&W 25 or 625 in .45 Colt, that is then cut for moonclips. Once this is done, it will not only accommodate .45 Schofield, but also .45 ACP and .45 GAP with moonclips only. Any other calibers would be too hot for it and a ka-boom would result.
The gun that can accept the most .45 caliber handgun rounds is the S&W 460 when mooncliped, accepting .45 Schofield, .45 Colt, .454 Casull, and .460 S&W without moonclips, and .45 ACP, .45 GAP, .460 Rowland and .45 Win Mag with moonclips. Of course, this is one of the biggest and heaviest revolvers on the market, and may not be practical for all purposes.
Another gun that is good for several calibers simply by adding cylinders is the Ruger Blackhawk in .45 Colt. Add a cylinder for .45 ACP, and get one more .45 ACP cylinder and have it reamed for .45 Win Mag. A company outside Lakeland Florida even makes them for .455 Webley for single action Rugers. The disadvantage is when it comes to shorter rounds without rims since they heaspace on the case mouth instead of on the moonclips. You'd have to get another cylinder to shoot .45 GAP, even thought it's only a bit shorter than .45 ACP.