One cheap thing you can try is to set up six (five?) targets, index your cylinder so you can repeat, and then fire one round at each target.
reload, repeat, reload, repeat.
If you have a cylinder problem you should have six(five?) tight groups of three shots, just printed at different places. If you have five(four?) tight groups and one target that looks pretty random, probably a cylinder problem.
If all six (five?) targets look random you might have a barrel problem - or it could be cylinder throats.
So the far left target, three rounds from chamber number 1, what have you got? Next target to the right, three rounds from your chamber #2, what have you got? Etc.