Though I heard that if you shoot a 454 inside your tent against a bear without hearing protection; there is a strong possibility that you'll go deaf --- For how long...I don't know.
If you shoot ANYTHING inside your tent without hearing protection you're going to go deaf for a while, and while most of your hearing will come back, some never will.
So I've owned a lot of guns but neither of these larger bore rounds in a revolver/handgun. I'm considering purchasing a 500 or 460 for bears when I go backpacking.
Ok, here's my advice...DON'T!
now, here's my explanation,
DON'T get one of them "for bears". You've never had one before, so don't get one for bears, get one because you are interested, curious, and want to see for yourself what they do, don't do, and what you can do, and not do, with them. "I want one to learn about it" is a perfectly good reason to get one, don't let anyone tell you otherwise or make you feel guilty, or that you need any other reason at all!
THEN, if you feel they're a good option, carry one "for bears".
I will admit I have no personal experience shooting either the .460 or the .500. But I do have experience shooting .44 and .45 Magnums, and also .45-70 in a handgun. I've also fired several .30 rifles one handed. Those big rounds have energy (on both ends) matching some traditional deer rifles, and recoil does matter.
There's no free lunch, big magnum class handguns are really replacements for rifles, much handier but more difficult to control for rapid follow up shots.
Between the two, I would choose the .460 as more practical/cost effective, because it can shoot .45 Colt rounds, and can use the full range of .45 caliber slugs, while the .500 has fewer options for ammo.
If you aren't experienced with big bore magnum level handguns, get one and welcome to the next level!! Its not something anyone can tell you about accurately, because we are all a little different, its something you have to experience personally.
Think of it a bit like this, you may have years of driving your car or pickup, but you don't just climb in an 18-wheeler and haul a load from Boston to Boise, nor do you jump in a formula 1 racer enter the Indy 500.
These are things that need to be learned, first. So, get that hand cannon of your choice, and ENJOY it, learn how to drive it well, THEN decide if its the right rig for your particular race.