US Cartridge Company was a true giant in the early years of self-contained metallic cartridges.
It was, IIRC, founded by a former Union civil war general, and became one of the largest (if not the largest) manufacturers of ammunition post 1900.
During World War I they produced enormous quantities of ammo for both the United States and for European allies.
In the 1920s they were bought by Winchester, and ammunition manufacturing was moved to New Haven.
Lesmok powder was, like other semi-smokeless powders, a combination of nitrocellulose and blackpowder.
Apparently it was also extremely dangerous to manufacture, as the combining process could have interesting effects. Winchester, owner of Lesmok, stopped manufacture after World War II.
Finally, IIRC, Les Smoke was the pen name of an early outdoors writer, back in the late 1800s.