There is no significant likelihood that the use of reloads in a shooting will, in and of itself, influence what happens after a shooing.
Combined with other facts, evidence of an intent to use extremely lethal ammunition, factory or hand loaded, could be used to develop an indication of state of mind, should there be any question about the "why" of the shooting.
More importantly, though, (1) if there is a shooting in which the evidence is unclear or contradictory, and (2) if the absence of gunshot residue on the person shot is used by the state as an indication either that (a) the actor's account is not credible or (b) that the shooting distance indicates against the existence of imminent danger, or both, and (3) if the rounds used would not have left GSR at the distance claimed by the actor while many others would, it would certainly benefit the actor to be able to introduce GSR tests of the ammunition used.
Due to court rulings associated with the admissibility of scientific trace evidence, it would be far better for the defendant to have used factory loads under such circumstances.
How likely? Well, there aren't very many SD shootings, to start with. If there is one inside your home, distance will most probably not be an issue.
But--go outside, shoot someone when there may be no witnesses, or just witnesses sympathetic to the person you shot, end up in a your-word-against-his-or-theirs situation, and end up dependent on your ability to show that GSR would not have been expected from your ammunition, and it's an issue.
At that point there will have been no advantage to not having used factory loads, and perhaps a very big disadvantage.
As for asking whether "anyone here" has "had the misfortune"-- realize that few have shot anyone, but if they have and if they have not yet been acquitted in a trial court and have if they do not have a strong basis to not risk a civil claim, they will have been responsibly advised to not talk about it to anyone.