I have a number or revolvers with other red dots on them and the front sights have caused no problems at all. Usually the red dot sits up just enough higher to not interfere.
Trijicon makes a set for Smith revolvers but you need the orange insert that is fit at the factory removed as the front sight fits in that dovetail. Rear sight requires at least a new leaf and quite possibly a new rear sight assy. The set up is expensive and prone to receive abuse due to their elevated status on the weapon.
Half life on the glow modules is around 10 years. So in 5 years you have half the brilliance.