Something like 90% of all deer are shot within 200 yards. There's at most a couple of inches of difference, if that much, from 150 to 180. Go two inches high at 100 and fuggeddaboutit.
"Brush-busting" is a myth. All bullets deflect, up to and including .45-70. The determining factor is the distance from the twig/branch to the target. The NRA folks published one set of results I recall form about forty or so yars back, in the old "Dope Bag". Unless the brush is very, very close to Bambi, don't shoot.
No telling how many deer my father killed with his '06; at least a hundred. That's up to 200 pounds, field-dressed weight. He used only the Hornady 150-grain Spire Point, at about GI M2 performance level.