Had them on my Kahr CM9, I haven’t handled the 2.O S&W yet but I can’t imagine 2.O’s grips being more aggressive than the Talon grips, the Talon’s are really aggressive.
Just to add, the Talon grips are absolutely excellent IMO, I was constantly re-adjusting my grip on the Kahr after a couple of rounds, the Talon grips/wraps cured that quickly.
If I were to say that there was a downside it would be IWB carry. Anytime I stood I had to make sure my shirt wasn’t sticking to the gun grips exposing my firearm.