I bought one of the first SR22s to hit the shelves, back when .22lr was cheap and plentiful. Between the wife and I, it ran through 2k rounds the first week. Lost count after that. I would estimate 5-7k rounds by now.
The recoil spring and mag springs need replacement now, but I just haven't gotten around to it yet. It's still a good shooter, but I have a failure to feed about every 50 rounds because of my lack of maintenance.
I fully expect mine to keep chugging along for another 100k rounds.