I've hunted them with a .22,.38,and a.41. Your quarry will not sit still very long so you have to gauge each possible shot before you shoot. Not a very big target, and they stay alive by being out of the talons and teeth of the animals that dine on them. Take your time, sit vewwy vewwy still, and success will come to you. I shoot 5 reds to every grey, but the stewpot doesn't discriminate. Tasty fare,just be careful not to get hair on the meat. Mepps used to buy the tails for spinner hackle, but unless you have hundreds, there isn't much dinero in it for you. Friends that tie flies would love to have them though. Get a "Mr. Squirrel" call and follow the instructions. When the treerat sits up and scolds you can knock him off his perch, and ALL the locals will scold at you. Funny to use, but it surely works.