I started in the mid 1970's as a young cop using revolvers on and off duty. I have had many and still carry them when appropriate. For the longest time, the standard duty round, country-wide was the 158 grain lead round nose. They sucked for many reasons, but revolver sights were regulated for bullets of that weight. Target wad cutters are close enough in weight to hit point of aim/point of impact. I carry +p in modern revolvers (Speer Gold Dot short barrel). In my aluminum S&W's and Colt Cobras I carry Hornady XTP 158 grain ammunition. They hit where the sights indicate they should and penetrate well. There's been a trend in recent years to recommend target wad cutters for defensive carry. You can find any number of articles, pro and con on the Internet. As always, the first rule is to have a gun. Most of the other stuff is angels dancing on the head of a pin. Good luck.