I have long considered converting a S&W 610 to 10mm Magnum since the ammo crunch, being that 41 mag is $80 a box now, but I'm concerned that the cylinder may not handle the pressure, even though it is N FRAME ***
It should handle the pressure just fine, since diameter-wise there's thicker metal surrounding the case than with .44 & .41 mag N-frame cylinders.
Check and see if custom wheelgun master Hamilton Bowen is still doing his magnum conversions on the 610 cylinders.
There's a bit more to it than just reaming them out. I considered this exercise on my all-original 6.5" S&W 610 (no dash, first-run model from 1990), and did a lot of research trying to find user experiences on the conversion.
The only negative I came across was from some posters who reported that while accuracy (using the moon clips) was good with the 10-Mag and standard 10mm (whether factory or handloads), groups opened up when shooting .40S&W ammo. This was attributed, apparently, to the longer bullet-jump from the extension of the interior chambers in the cylinder to accommodate the COAL of the longer magnum cartridge.
Ultimately I passed on the conversion. Not because there was anything wrong with it, it was just that a range acquaintance of mine paid really good money to acquire my 610 - offering, as they say, a sum of $$$ I couldn't refuse.
As I understand it now, first-run 610s in original condition are commanding huge premiums on gunsites like GunJoker.