Need a bit more information. What are you going to do with your rifle.
There are two ways I set up a rifle for hunting:
One:
Max. Point Blank Range. Determine the animal you are going to hunt. Lets take Elk for example. The vital are of an elk is aprox. 15 inches. Meaning that is the area containing the heart-lung area of the elk.
If you know the velocity and the BC of your bullet you could put it in a ballistic program and determine the range you could shoot, aiming at the center of the vital area and the bullet path would not be any higher then 7.5 inches or any lower then 7 inches.
That would give you the max. point blank range or a sighting in distance.
Second:
I use the G7 BR2 Ballistic range finder. I program the bullet, velocity, BC, etc into the range finder. I then sight my rifle in at 100 yards (you can pick any distance) and put the number in the BR2 also. When I range a target (up to 1400 yards) the BR2 tells me how much to come up or down to hit the target at that range. (I found this to be an accurate BC range finder)
You can combine the two and use your MPBZ into the BR2 and it will still tell you how much up or down you need.
Regardless you need more info besides a 300 WM w/180s.
You also need, if hunting, the type of bullet, for example, the Berger Hunt VLD bullets. They are designed to inter the animal a couple inches and completely come apart inside, totally destroying the nervous system. There is a limit on the range this will work. I use the Berger 210 Hunting VLD on my 300 WM. I contacted the Berger tec. staff and determined this works best =/> 1800 fps. With my rifle/load that would be 850 yards. Any thing past that the bullet may not work as intended.
You also need to know what animal you're hunting. The above works on deer/antelope/elk type animals. Bear/hogs have a different nervous system. With those you need a heavy bullet that will penetrate, expand, and hold together.
I know this doesn't answer your question but I hope it explains why we cant answer it.