Depending on the distance you're planning on shooting, you could have some problem with parallax.
Leupold, for instance, sets rimfire scopes for 60 yards, shotgun/muzzleloader scopes for 75 yards and centerfire scopes for 150 yards. The info is available, or buried depending on how well you like the site layout, on the Leupold site along with an explanation of parallax. Long story short - if you can keep your eye centered on the lens it won't matter, but if you move your head a little off-center your shots will wander even though the crosshairs stay on target.
John