As Shans mentioned the Sig P220 Stainless in 10mm. A few months ago a poster wanted to know which 10mm to buy. Some of us mentioned Sig was coming out with one in 10mm. There were some nay-sayers who believed Sig would not introduce a 10mm or at least not anytime soon.
Well, it now sounds like a solid recommendation and will be available in the near future. I think I will just stick with my two P220's in .45ACP. If I need a more powerful firearm, I will grab up my S&W .45 Colt.