NOTE: Humane was not an issue regarding the punkins... We wanted to mangle those Bad punkins but we were trying to find what was safer for in-the-house shooting in a family house in case something were to ever get that bad. We found the buck shot, slugs, pistol bullets (even Glasers etc.) were still penetrating through the entire set of walls which was set up in line like the walls of the house.
The Glasers penetrated the entire set of walls like an FMJ and we tried .380, 9mm and .45. I like the Glasers for what they do to punkins also but NOT for any safety features according to our tests. And, the buckshot of different sizes penetrated similar to a pistol bullet from a .25 or .32
My choice at home, in my Mossburg pump is #9 at 1540 fps in a plastic shot cup with a 2 3/4 shell. If I lived in a log home with interior log walls I'd feel better about some sort of buckshot in that case perhaps. But, after what I saw inside the punkins... I'd rather go for the smallest, fastest, shot in the deepest shot cup possible and if I was reloading, I'd test load some shot cups wrapped in a strand of dental floss to keep them from spreadin out as quickly.