I worked for a manufacturer of Thread locker (Loctite type stuff). You are experiencing transverse vibration-------------a common malady as old as sin.
I would guess this is a through hole thread pathway which means you may apply the blue thread locker to the fastener. If it is a blind hole, (one way in and one way out), apply the blue loctite to the side of the thread way and allow it to run to the bottom.
Anaerobics are liquid polyesters that harden in the prescence of metal ions and abscence of oygen. Just think blue. Blue is mil spec for medium strength. The breakaway torgue is greater than the prevailing torque and thus it is removable. The strength of a threadlocker is determined by the final durometer hardness.
Now, if the fram is aluminum you will need a primer to "fool" the threadlocker into thinking it is steel. If the grip is plastic and the female thread way of the grip is plastic without a steel insert, DO NOT USE A THREADLOCKER. Anaerobics will cause plastic to craze. In this case, use a little superglue and you will be good to go.