Took the S&W 627 3" V-comp out for its first test drive today. I have to add that this is my first revolver, otherwise I've just been shooting semiauto pistols. First, it is a really big heavy gun, heavier than my Valtro.45 or P7M8, which I shot today for comparison. Left the compensator on the barrel. The trigger was smooth out of the box and light, I'd guess around 4 pounds in single action. Tried Winchester white box FMJ 38 specials, couldn't shoot it well because I had trouble with my grip technique (my fault entirely - different from a semiauto). Switched over to .357 Winchester JHP white box, seemed kinda strange but though the recoil was more pronounced there seemed to be less muzzle flip? 
It seemed easier to shoot the .357's more accurately than the .38 specials. The ergonomics are a little bit off for me. I have small hands and had a tiny bit of trouble gripping the gun with the stock wooden grips. I'm going to probably going to get a set of Eagle checkered secret service grips and/or some rubber grips (anybody with suggestions). Overall, when I could grip correctly with .357 loads (and when my arm wasn't too tired), I could shoot the beast well. I think a little weight lifting, find a new hand grip technique (the instructional one Rob Leatham uses for his 1911 in the America Shooter series doesn't work well for yours truly), and new hands grips. I really like shooting this beast, and I'm going to probably shoot more 357's in the mix. Overall in my hands, the .45 was the most accurate, the 9mm the easiest, and the 357 I need more practice with but overall a very, very nice pistol.
It seemed easier to shoot the .357's more accurately than the .38 specials. The ergonomics are a little bit off for me. I have small hands and had a tiny bit of trouble gripping the gun with the stock wooden grips. I'm going to probably going to get a set of Eagle checkered secret service grips and/or some rubber grips (anybody with suggestions). Overall, when I could grip correctly with .357 loads (and when my arm wasn't too tired), I could shoot the beast well. I think a little weight lifting, find a new hand grip technique (the instructional one Rob Leatham uses for his 1911 in the America Shooter series doesn't work well for yours truly), and new hands grips. I really like shooting this beast, and I'm going to probably shoot more 357's in the mix. Overall in my hands, the .45 was the most accurate, the 9mm the easiest, and the 357 I need more practice with but overall a very, very nice pistol.