The Hornet is actually a pretty hot round for a handgun... I have a Taurus "Raging" ( same gun they put the 454 Casull in ) that worked fine in standard configuration, albeit quite muzzle heavy with it's full underlug 10" barrel with the tiny 22 caliber bore... I did a conversion to mine, using a Dan Wesson 6" barrel shroud, & made a custom out of it, mine has a 1 in 9" twist, & can now shoot up to 68 grain bullets
the "Raging" has a double cylinder lock, even though the Taurus bashers will cry foul, the "Raging" gun, is much stronger than a S&W K frame... just from my expirience with the Hornet in a revolver ( & I do have a couple S&W K frames, in 357 ) I doubt the K frame is up to a solid diet of lil rifle rounds
BTW... just converted a 22 mag revolver to center fire... this seems a much more practical solution, if someone would start producing 22 CCM cases again, or even 22 Velo-dog... as it was, I had a couple 100 steel cases turned for my revolver