With standard pressure ammo you should be able to shoot 25-30 or even 50 rounds per session (once every week or two). My hand doesn't hurt, but I also do a lot of yard work. Make sure you get a high grip on the backstrap.
Accuracy? I tend to shoot the snubbie high and right, which is the opposite of all my other guns. I don't shoot a snubbie for "groups," but I do try to hit a 10"wide x 12"tall rectangle most of the time at 30 feet. Doesn't always work.
I would practice a lot with cheap practice ammo that is the same pressure and weight as your carry load, i.e. 158-gr. FMJ if you carry 158-gr. Nyclads like vanfunk. Then you should get the same point of impact and learn how your revolver shoots/how you shoot your revolver.
Also, practice quick double taps, and double taps on two targets. If your range allows it, practice drawing from the pocket, and start with targets at five FEET. Then move out five feet at a time the better you get. Try strong hand point shooting, two-handed sighted, and one-handed "retention" position when the gun is by your side (be careful not to torch your blouse or shoot yourself in the ribs!) Also try shooting weak handed, kneeling, and seated.
Stand sideways to the target, draw, turn, and fire. If you dare, buy an inexpensive jacket at the Salvation Army and practice firing from within the pocket.
And practice reloading! This is important with a snubbie for two reasons. First, it only carries five rounds. I carry a rubber Bianchi Speed Strip in my offisde pocket with six rounds on it. Second, snubbies have short ejector rods, and you really have to slap those empties to get them out. +P rounds may be more difficult to remove, i.e. extract them with your fingers. I wouldn't bother carrying a speedloader -- it negates the joy of carrying a snubbie, which is its extremely low profile.
Hope this helps.
) reload if time and cover permits.