I had a Vaquero stainless, 7.5" in.44 Mag. Wound up trading it for a Super Blackhawk, as I wanted some thing with adjustable sights in .44 Mag.
All my Ruger SAs are new model guns (post 73 lockwork).
I have a pair of Blackhawk convertables in .45, a Blackhawk in .357, the Super in .44 Mag, a pair of Vaqueros, stainless, 4.5" in .45 Colt, a Vaquero (blue) 5.5" in .45 Colt, a Vaquero Bisley 5.5" in .45 Colt, and a
New Vaquero, blue 5.5" in .45 Colt.
(I can't find the pic of both, if I do, I'll post it) The
New Vaquero with a 5.5" barrel is the same length (butt to muzzle) as the
Vaquero with the 4.5" barrel (ok, its 4 5/8" I just call it 4.5" for ease of typing)
The New Vaquero is probably a bit stronger than the Colt or clones, BUT not enough stronger to matter, in the practical sense. IT is NOT strong enough to take the heavy "Ruger ONLY" .45 Colt loads developed for the Blackhawk back in the 60s & 70s. The Vaquero will handle these loads, being, essentially a fixed sight Blackhawk in size & strength.
Because I have spent 30 years shooting Blackhawks, and later Vaqueros, the New Vaquero (and Colts & clones) seem small to me. Its a personal thing. I have a good friend who has a safe full of Colts, and he feels the Blackhawk/Vaqueros are too big and clunky. (He's the guy I got my New Vaquero from)
New Vaqueros in .45 Colt are strong enough to handle the classic "max" load for .45 Colt, a 250gr @ 1000fps (or as close as your barrel length will get it). This level load was the listed max in reloading manuals for many decades, tested in Colt SAAs.
In a Colt size gun, that level of load is a handful. In the bigger, heavier Blackhawk and Vaquero, its not nearly so much recoil, and much more pleasant to shoot.
So, Recondo, which gun are you looking at? We got folks here can give you good advice on any of them.