I'd stay away from the 44 magnum one. The reasons are magazine capacity, penetration, rapid magazine changes, muzzle blast, and penetration. None of these favor the 44 magnum gun. The PC4 with Ghost Ring Sights is just built for the task of home defense. The 44 is built for hunting. Neither will do the other's job good enough in my opinion. (I also own a P-94 in 40 S&W so that prejudices me a bit)