Ruger and the .450BM
You can never tell about Ruger and how long they might carry a model/cartridge combo. The only certain thing is that if the firearm does not yield the profit they are seeking, it will be gone. Lot's of my favorite Rugers are gone. If I wanted one (and they did turn my head, but I resisted) I'd get one as funds allow. Once the surge ebbs, they might get scarce.
I hunt a Ruger .44 tube feed carbine quite a bit, and for 100 yd woods/treestand hunting, it is plenty of gun, and distinctly handy. My experience with it, and watching my Dad hunt the .44 mag in a Win carbine, has led me to conclude that the .44 is plenty of deer medicine in the woods. That said, the .450 BM is just more of the same. I don't see it as a 300 yd cartridge as somebody mentioned, but it is flatter than the .44. The .450BM numbers exceed the .44 mag by quite a bit. And the Ruger Ranch seems like a rough and tumble no nonsense hunting rifle. I'd loose the antitank gun muzzle brake, mount a Leupold 1-4x on it like jmr40 advised, and hunt.