I think one of the biggest mistakes shooters can make is changing their grip between shots. Wood grips are slicker than rubber, especially if your hands are sweating, making it difficult to maintain a consistent grip. Also, the wooden "target" grips that come standard with most revolvers are shaped all wrong for the human hand. Think about it; you're pinkie is your shortest finger, but where does it contact those wooden target grips? At the widest part, while your middle finger, the longest, is wrapped around the narrowest part of the grips. Makes no sense. Hogue's and Pachmyer's, etc., are better shaped to the human hand. But, as Bullrock says, we're all different. There is no perfect grip, stance, squeeze, etc. for every individual.