Smithy, I have a question.
What do you mean by "...is it more easily handled ..." ?
Are you asking which mechanism can safely contain more pressure, or which type of arm generates less recoil? Or have I missed the point entirely?
Generally, a longer barrel gives more velocity from the same cartridge loading. However, different examples of the same type of firearm will give different velocities depending on a multitude of internal - almost imperceptible - differences.
Black Mamba correctly cited the problem of 'barrel length'. Holster makers measure barrel length of revolvers from muzzle to face of cylinder, and pistols from muzzle to breach face. Ballisticians measure barrel length by the distance the bullet is actually pushed by the power charge. So ballistics barrel length is from the base of the bullet (where ever it may be) to the muzzle. This means in practical terms a revolver ALWAYS has a ballistic length longer than the nominal length and a pistol (semi-automatic or single shot) ALWAYS has a shorter ballistic length than nominal length.
If the question is pressure containment, SAAMI (Sporting Arms and Ammunition Manufacture's Institute) voluntary standards dictate the operating pressure of a .44 Magnum to be XX,XXX copper units of pressure. So any firearm manufactured by a SAAMI member and marked as .44 Magnum will handle that level of pressure safely. Which is not to say each sample will do so forever. (Feel free to check out
http://www.saami.org/specifications_and_information/publications/download/205.pdf
to see why I'm being vague about the actual numbers.)
Revolvers 'wear out' by some combination of two major factors. The top strap stretches over time and therefore the cylinder develops end play. This gets worse with age. Double action revolvers also develop a bit end play by the crane and the axis of the cylinder getting beat back and forth.
Single shot pistols, like the Contender or Encore, can - over time - shoot loose by means of distorting the holes in the frame being pounded out of round, and/or beating the connecting pin out of shape.
Neither condition typically causes a catastrophic failure where something actually 'blows up' in the classic bits and pieces flying all over creation. More common is excessive headspace where the loaded round will not fire reliably - because the firing pin isn't hitting the primer properly.
I'm not sure there is scientific evidence to show one style gets beat up faster than the other.
Does any of this speak to your question?