Back to zipspyder, who started this thread: Reading between your lines, I'm guessing that you buy ammo and don't reload; is that right? Reloading is what brings out the best in any caliber, especially the 45 Colt. While I have no doubt your Puma can handle some really stout +P loads, I'm thinking you would find the hottest loads from some of the niche manufacturers will be much more powerful and punishing than you need or want. You will find that your Puma is stronger than your shoulder as you get the snot kicked out of you. If you go that route, you will definitely need a good recoil pad. The standard 45 Colt load for many decades launched a 250 or 255 grain lead bullet at about 860 feet per second from a revolver. There has been a relatively recent trend to deviate from that standard in both directions: Low power loads meant for the popular cowboy-shooting-games; and quite the opposite, very high-pressure, heavy-bullet loads intended only for firearms that are much stronger than original Colt revolvers. But there is a wide performance gap between the standard loadings and the often-called, "Ruger Only", heavy loads. There seems to be little, if anything, that's being offered by the ammo companies, that falls within that performance gap. Yet there are some 45 Colt enthusiasts, myself included, that reload their own ammo, who have discovered that much of their favorite loads are in this realm of +P, but definitely not in the, "Buffalo-Bore", power level. Just because you can load your gun to the gills doesn't mean you will like it that way. Your Puma is likely quite a bit lighter than my Marlin, which means it will kick harder, all else being equal. My Marlin is probably stronger than my Vaquero and I have loaded both pretty heavily at times. Those loads in the Marlin have substantial recoil. Your Puma can likely handle hotter loads yet, but you will find that it kills on both ends.
If you do reload, I might have some further suggestions.....