While S&W makes/made a few models called the LadySmith, I don't particularly think they do much for a woman but give her "pretty grips" and a "fancy box". The two quintissential 5-shooters are the S&W J-frame (which can be had with an exposed hammer, a shrouded hammer, or an enclosed hammer) and the Ruger SP101. Taurus, Rossi, Charter Arms, and a few others also make similar guns.
However, my recommendation for concealed carry is one of the lightweight versions (ie, AirWeight or Titanium series). The pros are that they are lighter and easier to carry, while the biggest con is that they kick a lot more.
If pulling the trigger is tough (dry fire a few times at the shop), make sure to get one with an exposed hammer so you can cock it back if necessary.
I have a S&W 342ti; titanium, no hammer (as well as a S&W model 60 in .357). While the 342ti is tiny and extrememly easy to carry, it is tough to shoot well. The kick is horrible, and the double action only trigger is tough.
Finally, keep in mind that the lightweight versions are generally more money, and the titanium versions even more.