BPCR
You know that each and every gun is it's own self and may react well to a good load of another rifle or shoot it bad.
I purchased the Pedersoli Competition Sharps 1874 model about three years ago and tried many different loads.
A good standard load that does well in a lot of guns is 68 gr. of Goex Cartridge with the 535 grain Postell bullet.
To load the top loads you will need to have a very good set of dies like the RCBS Cowboy Dies. They have a larger expander die for lead bullets.
You will also have to shoot BP if you want the rifle to shoot as well as it can.
You also need a compression die, a powder funnel drop tube, and over powder wads.
It's also impossible to achieve the best accuracy without annealing your cases and fitting the bullets to your bore. If the rifle is a Pedersoli then it will most likely be a .458 which would require bullets at least .459 or .460 in diameter.
I suggest you purchase books like Mike Venturino Shooting Buffalo Rifles of the Old West.
It takes a lot of gun time to become a long range BP shooter and some shoot for years with out ever becoming one of the best. Do a lot of research and study the BPCR forum.
The two top powders now being used are Swiss 1 1/2 and KIK 2F. Best of Luck , Fairshake