Frangible ammo is highly debated.
Most Frangible ammo does not pass the FBI tests used to test the performance of defensive ammo. (ammo designed to stop threats)
The requirements are 12-18in of penetration in calibrated ballistic gel, both bare and when covered with 4 layers of extra heavy denim. Most feel the optimum is 15in of penetration in these tests.
The minimum is to ensure enough penetration to hit vital areas, the max is to limit over penetration of the target. The denim is to make sure the bullets function properly even when the target is wearing lots of clothing. (think winter)
Frangible ammo does not pass these tests, but the manufacturers claim other benefits.
While these benefits may or may not exist... There are no studies or tests to back up the claims. The only thing that is known... Is that the current testing standards work, as they are based on years of study by experts in many fields.
Basically, pistol rounds do not carry enough energy and velocity to take advantage of secondary wounding sources. Namely fluid cavitation that causes tissues to stretch past their elastic point, causing them to rip/tear, which means added damage.
A pistol bullet can only rely on direct contact damage... As in, the damage the bullet causes directly by ripping/cutting/crushing the tissues it comes into direct contact with.
So with a pistol round, good aim and reliable penetration are what you want... Modern hollow points deliver that.
In summary...
FMJ bullets penetrate very well... Too well in fact, at over 30 inches in most cases. They also offer less wounding ability, as they punch cleanly through and do little damage other than a straight hole. They work fine if your aim is good, but the potential for pass through of the target is very high.
Hollow points penetrate the right amount, the good ones anyway, and their expanding design allows for more wounding ability. Good aim is still a requirement.
Frangibles penetrate less, but have larger wound tracks. They may or may not penetrate bone well enough to work, and they may not reach vital areas on less than optimum shot angles. Due to these things, even with good aim, the bullet may not do a good job.
As was said before... Test you chosen rounds in your pistol. Enough for you to be comfortable that it works well in your pistol. For general practice use FMJ.
Cycle though your carry ammo on occasion, how often is your call, as it's good to practice with it from time to time. Another reason, is that repeated loading of the same bullet into the pistol's chamber, can cause the bullet to push deeper into the case, which causes increases in pressure when fired... Potentially damaging the gun, you, or someone else unintended. So if you have unloaded and reloaded the same bullet several times, retire it for range use later or put it in the bottom of the mag, and shoot it when you cycle through your ammo at some point. Well made ammo shouldn't have much issue, but things happen... So I avoid unloading my carry or defensive pistols unless absolutely necessary.
Most importantly...
Enjoy the sport.