Mehavey,
Check the image link in that post. It's telling me the image has been deleted.
Lots of match shooter have used 748 and other spherical propellants in the past. There's no theoretical reason I am aware of that they shouldn't work, other than it is apparently harder to make them temperature insensitive for a wide range of conditions, and some folks have had difficulty with keeping ignition consistent with the older formulations. Ramshot claims to have corrected that with their powders, and it is certainly the case that their TAC product has proven a favorite for many.
Sometime in the early 90's I decided to try Accurate 2520 one season. It's an older type spherical formulation. Unfortunately I could not tune it to work well with the 168 grain SMK's I was usually loading back then. I got about 1.25 moa from it, where 0.7 moa was what my stick powders were giving me. Then one day I decided to buy my first primer pocket deburring tool, and, lo and behold, the 2520 groups tightened up to 0.7 moa, same as the stick powders I'd been using in that gun (M1A). What I didn't know at the time was that CCI, in 1989 had altered their magnum primer formulation specifically for the Western Cannon spherical propellants like BL-C(2), and 2520 was apparently similar. If I had tried a magnum primer, I expect I'd have got the same results and saved a lot of flash hole deburring, but it didn't occur to me back then. Clearly, it was an ignition issue.
Fortunately, chronograph numbers give you a good hint about ignition consistency, with narrower velocity extreme spread tending to indicate better ignition performance. It's not that the powder with the smallest ES necessarily shoots best (at least, not at short range), but that any change you make that narrows the ES for a particular powder from whatever its starting point was, will have improved its ignition consistency. You may need to readjust the charge weight afterward for best accuracy, but when you do both, you usually end up with better accuracy, if you and your gun are up to taking advantage of it.