I have found Hodgdon HS-6 to be very reliable and accurate with moderate to full loads in the 9mm and .45 ACP. In fact, Hodgdon lists +P loads using this powder in the .45 ACP caliber. The spherical powder flows easily through the powder measure, and the powder is fairly clean burning. I have found the use of magnum primers to be unnecessary. It is also available in 8 lb. kegs, which makes it very economical.
I have tried Bullseye, Unique, and W231, but prefer the HS-6. Walt