To add to what Critter44 said: A few years ago, a friend of mine was driving with his girlfriend late one night, and pulled up at a traffic light in an inner-city area. A local scumbag decided that this was a good night for a hi-jack, and yanked open the passenger door. My friend was quick on the uptake - and on the draw! - and levelled his .38 Special snubbie across the car, into the BG's body, and fired one round, which effectively ended his assault. Unfortunately, his snubbie had a ported barrel, and the gases escaping from the ports went straight upward into his girlfriend's face, searing her nostrils and causing damage to her left eye. It took six months of medical treatment (including plastic surgery) to repair the damage.
Basing my decision on this experience, and on the possibility of having to fire from a retention position close to my body, which would point these ports up at my face, I've decided never to carry a ported firearm for self-defence. However, I still hunt with them, as under those conditions, self-inflicted flash-burns from the ports are unlikely.
(BTW, Critter, I think we'd get burned even with an unported revolver if fired from a close-to-the-body retention position: the flash from the cylinder/forcing-cone gap would still get to us, I think.)