For all but one of my bottom feeding auto's not gonna happen. The one I DO trim or square up the mouth is on my 10mm. I hunt with it on occasion, and have seen differences in the group sizes between trimmed and not trimmed.
I have been loading and shooting revolvers for most of my 50+years. I started out with plain jane 38 SPL before I was a teen, and as I grew older I got more and more interested in just how well I could make them shoot.
I look at it like this, I do all sorts of things to make a hunting rifle shoot sub MOA why should I not treat my other hunting ammo the same? Realistically I want them all to shoot as good as they can. Trimming isn't a huge deal as I usually do them in batches of around 100. I pull out a handful and measure. Then I pick the shortest one of the batch and set the trimmer to that one. I might get quite a bit off a few, simply square the mouth of more, and only polish a few more, but they all end up withing a couple of thousandths, and when I crimp they are all getting the same pressure on the bullets. When my Redhawk was scoped with a 4x Leupold and some carefully loaded hot 180gr Sierra's, I have shot plenty of 1" or slightly above groups at 100yds.
If you want to know what got me started in this process, it was reading Elmer Keith and how he worked up loads for accuracy. Granted he shot 100 times more than I probably ever will, but the techniques are still the same. Here is a link which contains some great reading. Scroll down a bit to the two write ups for handgun loading.
Elmer Keith Memorial Website
If you don't think that just the crimp can effect the accuracy of a load, here is a picture of the identical load with only the crimp changed,
The group on the left was too much. The ones on the right were backed off only about 1/8 of a turn if that much. They were shot at 40yds, standing and using a two hand hold. The revolver was my friends S&W 657 Classic Hunter in 41 magnum of my friends. The high and low ones were totally my fault due to the smooth trigger it has. That was also the first time I had shot it. The point is that a little bit of difference, can make a big difference.