Nipples
I had the same problem with my Piettas 60's,58 and Starr. The Nipples would go in or out very difficult right from the start to the finish. Hard enough that I thought they were crossed. I read some where online ,possibly this forum, that Pietta uses a die and tap that is not finished. Exactly what that means I don't know, maybe slightly under size or perhaps a little rougher finish to make threads a bit tighter to prevent loosening. I got a tap and die set from a place in Brooklyn ,did all my nipples and cylinders and never had another problem.
My piettas are less than 5 years old and the thread size is 6x75