Back in the 60s I became quite a disciple of the magnum rifle craze, so I wrote a letter to Roy Weatherby asking him why his high velocity projectiles supposedly "killed" game quicker than a slower bullet. I was surprised to receive a personal letter from him describing what I believe he called hydrostatic shock, or the effect of very high velocity bullets on some type of water-bearing mass, i.e., animals (and it follows that two legged animals would fall into that category). He was convinced that such an effect occurred. I personally believe there is something to this line of reasoning IN HIGH VELOCITY RIFLE BULLETS. Written accounts of military snipers often told of upper torso shots (when a cranial shot was impossible) that dropped a person instantly.
I am less convinced that a pistol bullet has the type of "energy transfer" that occurs in high velocity projectile strikes.
Therefore, for me, I usually rely on one of three calibers: 45 ACP, 45 Colt, or 44 Special. I do use some type of premium HP bullet in each, thereby covering my fanny (hopefully) by using big as well as expanding. As I said in a previous post, I am less concerned with "this bullet" or "that bullet" and have become VERY concerned with my ability to place my shot where I want it to go under any conceivable situation.
From competence comes security. It does not come from buying the latest magic bullet. Therefore, for me, fast or slow is really a moot point
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The real democratic American idea is, not that everyman shall be on a level with every other, but that every one shall have liberty, without hindrance, to be what God made him . . . H.W. Beecher